Tirzepatide Improved Markers of Islet Cell Function and Insulin Sensitivity in People With T2D (SURPASS-2).

Juan P FriasChristophe De BlockKatelyn BrownHui WangMelissa K ThomasMeltem ZeytinogluJuan M Maldonado

Published in: The Journal of clinical endocrinology and metabolism (2024)

In this post hoc analysis, improvements in HbA1c and weight loss were consistent and significantly higher with tirzepatide, regardless of baseline β-cell function and insulin resistance, compared with semaglutide.

Keyphrases

weight loss
insulin resistance
bariatric surgery
adipose tissue
high fat diet
metabolic syndrome
roux en y gastric bypass
polycystic ovary syndrome
gastric bypass
skeletal muscle
high fat diet induced
glycemic control
body mass index
physical activity
obese patients