The IGF-Axis and Diabetic Retinopathy Before and After Gastric Bypass Surgery.
Troels BrynskovCaroline Schmidt LaugesenAndrea Karen FloydJan FrystykTorben Lykke SørensenPublished in: Obesity surgery (2017)
In obese T2D patients, bioactive IGF is a potential biomarker for DR and levels tended to increase 3 months after bariatric surgery. IGFBP-1 increased while IGFBP-3 and total IGF-II decreased postoperatively, but these changes were unassociated with the development of DR. Markers of the metabolic syndrome improved.
Keyphrases
- diabetic retinopathy
- metabolic syndrome
- gastric bypass
- weight loss
- end stage renal disease
- obese patients
- newly diagnosed
- pi k akt
- ejection fraction
- binding protein
- roux en y gastric bypass
- minimally invasive
- growth hormone
- chronic kidney disease
- adipose tissue
- editorial comment
- optical coherence tomography
- bariatric surgery
- coronary artery bypass
- cardiovascular disease
- uric acid
- percutaneous coronary intervention
- skeletal muscle
- atrial fibrillation
- cell proliferation
- coronary artery disease
- signaling pathway
- patient reported