Real-world persistence of multiple sclerosis disease-modifying therapies.

Emma Clare Tallantyre Chu-Yueh GuoJoseph L J FroudFrederika A St JohnValerie M AndersonTarunya ArunLauren BuckleyNikos EvangelouHelen L FordIan GaleaSumi GeorgeOrla M GrayAimee M HibbertMo HuStella E HughesGillian IngramSeema KalraChia-Hui E LimJoela T M MathewsGavin V McDonnellNaomi MescallSam NorrisStephen J RamsayClaire M RiceMelanie J RussellMarianne J Shawe-TaylorThomas E WilliamsKatharine E HardingNeil P Robertson

Published in: European journal of neurology (2024)

Immune reconstituting DMTs may have the highest potential to offer a single treatment for relapsing MS. Comparative data on DMT persistence and reasons for discontinuation are valuable to inform treatment decisions and in personalizing treatment in MS.

Keyphrases

multiple sclerosis
machine learning
systemic lupus erythematosus
combination therapy
white matter
risk assessment
big data
deep learning
artificial intelligence
replacement therapy