Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder-implications of a copy number variation involving DPP10.
Annisa Shui Lam MakAnnie Ting Gee ChiuGordon Ka Chun LeungChristopher Chun Yu MakYoyo Wing Yiu ChuGary Tsz Kin MokWing Fai TangKelvin Yuen Kwong ChanMary Hoi Yin TangElizabeth Tak-Kwong Lau YimKin Wai SoVictoria Qinchen TaoCheuk Wing FungVirginia Chun Nei WongMohammed UddinSo Lun LeeChristian R MarshallStephen W SchererAnita Sik Yau KanBrian Hon-Yin ChungPublished in: Molecular autism (2017)
The DPP10 duplication is likely a benign CNV polymorphism enriched in Southern Chinese with a population frequency of ~1%. This highlights the importance of using ancestry-matched controls in interpretation of aCGH findings.