Sildenafil-evoked photoreceptor oxidative stress in vivo is unrelated to impaired visual performance in mice.

Bruce A BerkowitzRobert H PodolskyKaren Lins ChildersAicha SaadaneTimothy S KernRobin RobertsHailey OldsJoydip JoyCollin RichardsTilman RosalesMichael SchneiderBrennan SchillingArthur OrchanianEmma GrafficeKenan SinanHaohua QianLamis Harp

Published in: PloS one (2021)

The sildenafil-induced spatiotemporal pattern of oxidative stress in photoreceptors dominated by rods was unrelated to impairment of cone-based visual performance in wildtype mice.

Keyphrases

oxidative stress
diabetic rats
high fat diet induced
pulmonary hypertension
pulmonary arterial hypertension
dna damage
cord blood
ischemia reperfusion injury
induced apoptosis
high glucose
insulin resistance
metabolic syndrome
heat shock
drug induced
signaling pathway
stress induced