Exosome-mediated delivery of miR-204-5p inhibits tumor growth and chemoresistance.

Surui YaoYuan YinGuoying JinDan LiMin LiYaling HuYuyang FengYuhang LiuZehua BianXue WangYong MaoJia ZhangZhimeng WuZhaohui Huang

Published in: Cancer medicine (2020)

In this study, we confirmed that exosomal miR-204-5p could efficiently inhibit cancer cell proliferation, induce apoptosis and increase chemosensitivity by specifically suppressing the target genes of miR-204-5p in human cancer cells.

Keyphrases

cell proliferation
endothelial cells
papillary thyroid
oxidative stress
signaling pathway
genome wide
cell cycle
squamous cell
young adults
childhood cancer
cancer stem cells