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Cortical microvascular blood flow velocity mapping by combining dynamic light scattering optical coherence tomography and two-photon microscopy.

Qi PianMohammed AlfadhelJianbo TangGrace V LeeBaoqiang LiBuyin FuYagmur AyataMohammad Abbas YaseenDavid A BoasTimothy W SecombSava Sakadzic
Published in: Journal of biomedical optics (2023)
The proposed framework may serve as a useful tool for quantitative analysis of large microvascular datasets obtained by OCT and 2PM in studies involving normal brain functioning, progression of various diseases, and numerical modeling of the oxygen advection and diffusion in the realistic microvascular networks.
Keyphrases
  • blood flow
  • optical coherence tomography
  • high resolution
  • diabetic retinopathy
  • particulate matter
  • air pollution
  • single molecule
  • optic nerve
  • white matter
  • high speed
  • rna seq
  • mass spectrometry
  • label free
  • single cell