The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex.

Magdalena GierulaIsabelle I Salles-CrawleySalvatore SantamariaAdrienn Teraz-OroszJames T B CrawleyDavid A LaneJosefin Ahnström

Published in: Journal of thrombosis and haemostasis : JTH (2019)

FVa plays a central role in the formation of its inactivation complex. Furthermore, membrane proximal interactions among FVa, APC, and protein S are essential for its cofactor function.

Keyphrases

protein protein
amino acid
binding protein