Genetic mutations in adaptive evolution of growth-independent vancomycin-tolerant Staphylococcus aureus.

Pilong LiuZehua HaoMiaomiao LiuMingze NiuPeng SunShunhua YanLixiu Zhao Xin Zhao

Published in: The Journal of antimicrobial chemotherapy (2021)

Our results demonstrate that genetic mutations are responsible for emergence of phenotypic tolerance and formation of vancomycin tolerance may lie in cell wall changes in S. aureus.

Keyphrases

cell wall
staphylococcus aureus
methicillin resistant staphylococcus aureus
genome wide
copy number
dna methylation
pseudomonas aeruginosa
gene expression
candida albicans