Augmenting bacterial similarity measures using a graph-based genome representation.
Vivek RamananIndra Neil SarkarPublished in: mSystems (2024)
Given the prevalence and necessity of the 16S rRNA measure in bacterial identification and analysis, this additional analysis adds a functional and synteny-based layer to the identification of relatives and clustering of bacteria genomes. It is also of computational interest to model the bacterial genome as a graph structure, which presents new avenues of genomic analysis for bacteria and their closely related strains and species.