Clostridium bolteae is elevated in neuromyelitis optica spectrum disorder in India and shares sequence similarity with AQP4.

Lekha Pandit Laura Michelle CoxChaithra MalliAnitha D'CunhaTimothy RooneyHrishikesh LokhandeValerie WillocqShrishti SaxenaTanuja Chitinis

Published in: Neurology(R) neuroimmunology & neuroinflammation (2020)

Our study described elevated levels of C bolteae associated with AQP4+ NMOSD among Indian patients. It is possible that this organism may be causally related to the immunopathogenesis of this disease in susceptible individuals.

Keyphrases

end stage renal disease
spectrum disorder
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors