Antiprostate Cancer Activity of Ineupatolide Isolated from Carpesium cernuum L.

Yuan-She HuangJing-Xin MaoLai ZhangHong-Wei GuoChen Yan Min Chen

Published in: BioMed research international (2021)

T-21 exhibits antiproliferation effects on PC-3 cells by promoting apoptosis and arresting the cell cycle in the G2 and S phases. The possible mechanism underlying its potential therapeutic effects against prostate cancer is related to the AKT/xlAP pathway.

Keyphrases

cell cycle
cell proliferation
prostate cancer
papillary thyroid
radical prostatectomy
oxidative stress
signaling pathway
endoplasmic reticulum stress
squamous cell
cell death
cell cycle arrest
squamous cell carcinoma
pi k akt
childhood cancer