Intracranial hemorrhage in large vessel occlusion patients receiving endovascular thrombectomy with or without intravenous alteplase: a secondary analysis of the DIRECT-MT trial.
Xiaowei HuYu ZhouJohanna OspelFeirong YaoYizhi LiuHui WangBo LiPinjing HuiPengfei YangYongwei ZhangLei ZhangZifu LiPengfei XingHuaizhang ShiHongxing HanShouchun WangQi FangJianmin Liunull nullPublished in: Journal of neurointerventional surgery (2022)
Our data showed that in the DIRECT-MT trial, alteplase did not increase overall ICH for large vessel occlusion patients treated with thrombectomy, but it increased the parenchymal hematoma rate.