Plasma miR-199a-5p is increased in neutrophilic phenotype asthma patients and negatively correlated with pulmonary function.
Yali HuangShengding ZhangXiaoyu FangLu QinYu FanDandan DingXiansheng LiuMin XiePublished in: PloS one (2018)
Plasma miR-199a-5p was increased in neutrophilic asthma and negatively correlated with pulmonary function, which suggests that miR-199a-5p actively contributes to disease pathogenesis by modulating the inflammatory process and transferring the signal from inflammatory cells to structure cells.
Keyphrases
- induced apoptosis
- cell cycle arrest
- chronic obstructive pulmonary disease
- end stage renal disease
- oxidative stress
- lung function
- ejection fraction
- signaling pathway
- newly diagnosed
- chronic kidney disease
- endoplasmic reticulum stress
- cell death
- prognostic factors
- peritoneal dialysis
- allergic rhinitis
- air pollution
- cell proliferation
- pi k akt
- cystic fibrosis
- patient reported