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Microneedles for drug delivery: recent advances in materials and geometry for preclinical and clinical studies.

Nae-Won KangSungho KimJae-Young LeeKi-Taek KimYuji ChoiYujeong OhJongchan KimDae-Duk KimJung-Hwan Park
Published in: Expert opinion on drug delivery (2021)
The design of MAPs needs to be determined based on what properties would be effective for the target diseases and purposes. In addition, in preclinical studies, it is necessary to consider not only the novelty of the formulations but also the feasibility of clinical application. Currently, clinical studies of microneedles loaded with various drugs and vaccines are in progress. When the regulation of pharmaceutical microneedles is established and more clinical studies are published, more drugs will be developed as microneedle products and clinical research will proceed. With these considerations, the microneedle array patch will be a better option for drug delivery.
Keyphrases
  • drug delivery
  • cancer therapy
  • drug release
  • cell therapy
  • high throughput
  • drug induced
  • systematic review
  • mass spectrometry
  • case control
  • mesenchymal stem cells