Kaempferol-Enhanced Migration and Differentiation of C2C12 Myoblasts via ITG1B/FAK/Paxillin and IGF1R/AKT/mTOR Signaling Pathways.

Tzyh-Chyuan HourNguyen Thai Lan NhiI-Ju LaiChih-Pin ChuuPei-Chen LinHsi-Wen ChangYing-Fang SuChung-Hwan ChenYu-Kuei Chen

Published in: Molecular nutrition & food research (2024)

Together, the findings suggest that KMP enhances the migration and differentiation of C2C12 myoblasts through the ITG1B/FAK/paxillin and IGF1R/AKT/mTOR pathways. Thus, KMP supplementation might potentially be used to prevent or delay age-related loss of muscle mass and help maintain muscle health.

Keyphrases

signaling pathway
pi k akt
cell proliferation
public health
healthcare
cell migration
binding protein
epithelial mesenchymal transition
induced apoptosis
mental health
skeletal muscle
growth hormone
health information
oxidative stress
human health
health promotion