Therapeutic plasma exchange in paediatric neurology: a critical review and proposed treatment algorithm.

Michael Eyre Yael HacohenCarmen BartonCheryl HemingwayMing Lim

Published in: Developmental medicine and child neurology (2018)

Studies investigating therapeutic plasma exchange (TPE) are small and mainly uncontrolled. They provide evidence for the efficacy of TPE in childhood neuro-inflammatory conditions. TPE is generally well tolerated provided key adverse effects are anticipated and avoided. Systematic dosing and objective assessment of treatment effect should be priorities for future research.

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