Stroke Recovery-Related Changes in Cortical Reactivity Based on Modulation of Intracortical Inhibition.
Sylvain HarquelAndéol Cadic-MelchiorTakuya MorishitaLisa FleuryAdrien WitonMartino CeroniJulia BrüggerNathalie Heidi MeyerGiorgia G EvangelistaPhilip EggerElena BeanatoPauline MenoudD Van De VilleSilvestro MiceraOlaf BlankeBertrand LégerJan AdolphsenCaroline JagellaChristophe ConstantinVincent AlvarezPhilippes VuadensJean-Luc TurlanAndreas MühlChristophe BonvinPhilipp J KochMaximilian J WesselFriedhelm Christoph HummelPublished in: Stroke (2024)
The present results revealed an abnormal motor cortical reactivity in patients with stroke, which was driven by perturbations and longitudinal changes within the intracortical inhibition system. They support the view that disinhibition in the ipsilesional motor cortex during the first-week poststroke is beneficial and promotes neuronal plasticity and recovery.