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Subpopulation Differences in the Cardiovascular Efficacy of Long-Acting Glucagon-Like Peptide 1 Receptor Agonists in Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis.

Liyun HeNa YangLingling XuFan PingWei LiYuxiu LiHuabing Zhang
Published in: Diabetes therapy : research, treatment and education of diabetes and related disorders (2020)
Our analysis suggested no subpopulation differences in the cardiovascular efficacy of long-acting GLP-1RAs among stratified subpopulations, and favorable trends were only observed in the subpopulation with established CVD. These findings may have implications for the management of long-acting GLP-1RAs across subpopulations of patients with T2DM.
Keyphrases
  • wild type
  • metabolic syndrome
  • skeletal muscle
  • insulin resistance
  • weight loss