Social experience and sex-dependent regulation of aggression in the lateral septum by extrasynaptic δGABAA receptors.
Johnathan M BorlandJames C WaltonAlisa NorvelleKymberly N GranthamLauren M AianiTony E LarkinKatharine E McCannH Elliott AlbersPublished in: Psychopharmacology (2019)
These data suggest that social experience can have profound effects on the neuronal mechanisms mediating aggression, especially in males, and that δ extrasynaptic GABAA receptors may be an important therapeutic target in disorders characterized by high levels of aggression.