A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Yu FuZhili XinZiji LingHanyu XieTao XiaoXin ShenJialin LinLing XuHongbing JiangPublished in: Molecular medicine (Cambridge, Mass.) (2021)
Our study identifies that the interaction loop between CREB1 and miR-181a-5p plays a crucial role in regulating the pathophysiologic features of FD BMSCs. MiR-181a-5p may be a potential therapeutic target for the treatment of FD.