Circadian Variation in Human Milk Composition, a Systematic Review.

Merel F ItalianerEva F G NaninckJorine A RoelantsGijsbertus T J van der HorstIrwin K M ReissJohannes Hans B van GoudoeverKoen F M JoostenInês Chaves Minerva J Taeubert

Published in: Nutrients (2020)

A total of 83 reports assessing the circadian variation in the concentration of 71 human milk components were included. Heterogeneity among studies was high. The methodological quality varied widely. Significant circadian variation is found in tryptophan, fats, triacylglycerol, cholesterol, iron, melatonin, cortisol, and cortisone. This may play a role in the child's growth and development in terms of the biological clock.

Keyphrases

human milk
low birth weight
preterm infants
preterm birth
emergency department
quality improvement
electronic health record