Heart rate variability and fatigue in MS: two parallel pathways representing disseminated inflammatory processes?

Guadalupe GarisMichael HauptsThomas DuningHelmut Hildebrandt

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

We discuss the results of this review in relation to our model of fatigue and propose several observational and experimental studies that could be conducted to gain a better insight into whether fatigue and HRV can be interpreted as a common pathway, both reflecting activated autoimmune processes in MS patients.

Keyphrases

heart rate variability
multiple sclerosis
mass spectrometry
sleep quality
heart rate
ejection fraction
newly diagnosed
prognostic factors
oxidative stress
blood pressure
physical activity