JAK/STAT3 regulated global gene expression dynamics during late-stage reprogramming process.

Ling WangZongliang JiangDelun HuangJingyue DuanChang HuangShannon SullivanKaneha ValiYexuan YinMing ZhangJill WegrzynXiuchun Cindy TianYoung Tang

Published in: BMC genomics (2018)

Our study illustrates novel insights for JAK/STAT3 promoted pluripotency establishment, which are valuable for further improving the naïve-pluripotent iPSC generation across different species including humans.

Keyphrases

gene expression
dna methylation
transcription factor
genetic diversity
induced pluripotent stem cells