Up-regulated small-conductance calcium-activated potassium currents contribute to atrial arrhythmogenesis in high-fat feeding mice.

Wei-Chung Tasi Yi-Hsiung LinChia-Hao KuoShih-Jie JhuoRuo-Yun ShihChun-Chieh WuI Hsin LiuTien-Chi HuangRen-Ming LiuTsung-Hsien Lin Ho-Ming SuWen-Ter LaiChien-Hung Lee Bin-Nan Wu Shien-Fong Lin Hsiang-Chun Lee

Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)

Up-regulation of apamin-sensitive SK currents plays a partial role in the atrial arrhythmogenicity of HFD mice.

Keyphrases

high fat diet induced
atrial fibrillation
left atrial
catheter ablation
type diabetes
insulin resistance
metabolic syndrome
mitral valve
left ventricular