Right ventricular load and contractility in HIV-associated pulmonary hypertension.
Arun RajaratnamSofiya RehmanPrerna SharmaVikas K SinghMelissa I SaulRebecca R VanderpoolMark T GladwinMarc A SimonAlison MorrisPublished in: PloS one (2021)
PLWH with PH (PAH or PVH) were more likely to have a detectable HIV viral load and lower CD4 count at the time of RHC. PLWH with PAH or PVH had increased RV afterload, normal RV contractility, with preserved RV-PA coupling suggestive of an early onset, mild, and compensated form of PH. These results should be confirmed in larger studies.
Keyphrases
- early onset
- mycobacterium tuberculosis
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- pulmonary hypertension
- human immunodeficiency virus
- late onset
- hepatitis c virus
- hiv aids
- men who have sex with men
- smooth muscle
- polycyclic aromatic hydrocarbons
- south africa
- pulmonary artery
- pulmonary arterial hypertension
- peripheral blood