Adjunctive Statistical Standardization of Adjuvant Estrogen Receptor and Progesterone Receptor in Canadian Cancer Trials Group MA.27 Postmenopausal Breast Cancer Trial of Exemestane Versus Anastrozole.

Judith-Anne W ChapmanJane BayaniSandip SenGuptaJohn M S BartlettTammy PiperMary Anne QuintayoShakeel VirkPaul E GossJames N Ingle Matthew J Ellis George W Sledge George T Budd Manuela RabaglioRafat H AnsariRichard TozerDavid P D'SouzaHaji ChalchalSilvana SpadaforaVered Stearns Edith A Perez Karen A Gelmon Timothy J WhelanCatherine ElliottLois E Shepherd Bingshu E Chen Karen J Taylor

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)

Adjunctive statistical standardization differentiated quantitated levels of ER and PgR. Patients with higher ER- and PgR-standardized units had superior DDFS compared with those with HSCOREs and %+ ≤-1.

Keyphrases

estrogen receptor
papillary thyroid
early stage
squamous cell
study protocol
phase iii
clinical trial
bone mineral density
breast cancer risk
phase ii
metastatic breast cancer
binding protein
open label
body composition