Intraoperative mapping of epileptogenic foci and tumor infiltration in neuro-oncology patients with epilepsy.
Dongqing SunEline V SchaftBibi M van StempvoortTineke A GebbinkMaryse A Van't KloosterPieter van EijsdenSandra M A van der SalmJan Willem DankbaarMaeike ZijlmansPierre A J T RobePublished in: Neuro-oncology advances (2024)
Complete resection of epileptogenic foci in ioECoG may promote seizure control in IDH-mutant gliomas. The cohort size of IDH-wildtype tumors was too limited to draw definitive conclusions. Interictal spikes may indicate tumor infiltration even when this area appears normal on MRI. Integrating electrophysiology guidance into oncological tumor surgery could contribute to improved seizure outcomes and precise guidance for radical tumor resection.