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Stimulator of interferon genes/Interferon regulatory factor 3 (STING-IRF3) and inflammasome-activation mediated pyroptosis biomarkers: a network of integrated pathways in diabetic nephropathy.

Omnia Safwat El-DeebYasser Mostafa HafezAmira Kamel EltokhyMarwa Mahmoud AwadRehab Ahmed Ahmed El-ShaerMuhammad Tarek Abdel GhafarMarwa Mohamed Atef
Published in: Journal of diabetes and metabolic disorders (2023)
The study documented the forthcoming role of STING in DN progression and its positive correlation with inflammasome-activation mediated pyroptosis biomarkers throughout its three different stages; launching new horizons in DN pathogenesis by highlighting its role as a reliable prognostic biomarker.
Keyphrases
  • diabetic nephropathy
  • dendritic cells
  • nlrp inflammasome
  • transcription factor
  • genome wide
  • gene expression
  • dna methylation
  • genome wide identification