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A convenient UHPLC-MS/MS method for routine monitoring of plasma and brain levels of nicotine and cotinine as a tool to validate newly developed preclinical smoking model in mouse.

Mohammad A KaisarRaja Reddy KallemRavi K SajjaAli Ehsan SifatLuca Cucullo
Published in: BMC neuroscience (2017)
This method was successfully utilized to validate a newly developed preclinical smoking model in mice.
Keyphrases
  • smoking cessation
  • ms ms
  • cell therapy
  • clinical practice
  • type diabetes
  • simultaneous determination
  • high fat diet induced
  • mass spectrometry
  • skeletal muscle
  • mesenchymal stem cells
  • high resolution mass spectrometry