Inhibition of Fap Promotes Cardiac Repair by Stabilizing BNP.

Yuxi SunMengqiu MaDandan CaoAncheng ZhengYiying ZhangYang SuJianfang WangYanhua XuMi ZhouYansong TangYifan LiuTeng MaAoyuan FanXiaoying ZhangQiaoling ZhuJiachen QinChunyang MoYawei XuLi Zhang Dachun Xu Rui Yue

Published in: Circulation research (2023)

This study identifies Fap as a negative regulator of cardiac repair and a potential drug target to treat MI. Inhibition of Fap stabilizes BNP to promote angiogenesis and cardiac repair.

Keyphrases

left ventricular
endothelial cells
transcription factor
gene expression
climate change
atrial fibrillation