Login / Signup

Estrogen inhibits autophagy and promotes growth of endometrial cancer by promoting glutamine metabolism.

Wen-Jie ZhouJie ZhangHui-Li YangKe WuFeng XieJiang-Nan WuYan WangLi YaoYan ZhuangJiang-Dong XiangAi-Jun ZhangYin-Yan HeMing-Qing Li
Published in: Cell communication and signaling : CCS (2019)
CB-839 triggers autophagy and restricts growth of UEC by suppressing ER/Gln metabolism, which provides new insights into the potential value of CB-839 in clinical treatment of estrogen-related UEC.
Keyphrases
  • endometrial cancer
  • estrogen receptor
  • cell death
  • endoplasmic reticulum stress
  • signaling pathway
  • oxidative stress
  • human health
  • climate change
  • combination therapy
  • endoplasmic reticulum