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Pericytes in Vascular Development.

Laura Beth PayneMaruf HoqueClifton HoukJordan DardenJohn C Chappell
Published in: Current tissue microenvironment reports (2020)
Recent advances in pericyte-focused tools and models have illuminated critical aspects of pericyte biology including their roles in vascular development.Pericytes likely collaborate with endothelial cells undergoing vasculogenesis, initiating direct interactions during sprouting and intussusceptive angiogenesis. Pericytes also provide important regulation of vascular growth including mechanisms underlying vessel pruning, rarefaction, and subsequent regrowth.
Keyphrases
  • endothelial cells
  • blood brain barrier
  • vascular endothelial growth factor