Toxic leukoencephalopathy with axonal spheroids caused by chemotherapeutic drugs other than methotrexate.

Ka Young LimSeong-Ik KimHyunhee KimJeongwan KangJin Woo ParkJae Kyung WonDong-Yeop ShinHye-Kyung Park

Published in: BMC neurology (2022)

The neuropathology found in the presented cases had the characteristic features of toxic leukoencephalopathy (chemobrain). Our cases showed that toxic leukoencephalopathy can also be caused by chemotherapy drugs other than methotrexate.

Keyphrases

high dose
spinal cord injury
squamous cell carcinoma
radiation therapy
optical coherence tomography
rectal cancer