The transient receptor potential melastatin 4 channel inhibitor 9-phenanthrol modulates cardiac sodium channel.

Jian-Wen HouYu-Dong FeiWei LiYi-He ChenQian WangYing XiaoYue-Peng WangYi Gang Li

Published in: British journal of pharmacology (2018)

Our results indicate that 9-phenanthrol modulates the gating properties of cardiac sodium channels and inhibits INaL and INaP , which may contribute to its antiarrhythmic and cardioprotective effects.

Keyphrases

left ventricular
cerebral ischemia
atrial fibrillation
climate change
binding protein
blood brain barrier
catheter ablation