Association between glucose intolerance and chemotherapy-induced lung injury in patients with lung cancer and interstitial lung disease.

Toshihito OtaniKakuhiro YamaguchiSatoshi NakaoShinjiro SakamotoYasushi HorimasuTakeshi MasudaShintaro MiyamotoTaku NakashimaHiroshi IwamotoKazunori FujitakaHironobu HamadaNoboru Hattori

Published in: Cancer chemotherapy and pharmacology (2021)

Glucose intolerance (e.g., HbA1c level ≥ 5.8%) may be a risk factor of cytotoxic chemotherapy-induced lung injury, which might be associated with elevated AGE production due to hyperglycemia.

Keyphrases

chemotherapy induced
interstitial lung disease
systemic sclerosis
blood glucose
rheumatoid arthritis
idiopathic pulmonary fibrosis
risk factors
blood pressure
weight loss
insulin resistance