Automated radiolabelling of [ 68 Ga]Ga-PSMA-11 (gallium ( 68 Ga)-gozetotide) using the Locametz® kit and two generators.

Elke A van BrandwijkElse A AalbersbergArman S HosseiniAlwin D R HuitemaJeroen J M A Hendrikx

Published in: EJNMMI radiopharmacy and chemistry (2024)

Ga]Ga-PSMA-11 using the Locametz® kit with higher gallium-68 activity than specified in the SmPC results in a product that is in compliance with the Ph. Eur. monograph and has a shelf-life of 6 h at room temperature. Radiolabelling with two generators proved possible and resulted in a product with similar quality but with much higher efficiency.

Keyphrases

pet ct
room temperature
positron emission tomography
machine learning
computed tomography
pet imaging