TSPO2 translocates 5-aminolevulinic acid into human erythroleukemia cells.

Hana Manceau Sophie D Lefevre Arienne Mirmiran Claude Hattab Hugo R Sugier Caroline Schmitt Katell Peoc'h Herve Puy Mariano Anibal Ostuni Laurent Gouya Jean-Jacques Lacapere

Published in: Biology of the cell (2020)

This is the first characterisation of molecular mechanisms involving a new actor in ALA transport in ALA-induced PPIX accumulation in erythroleukemia cells, which could be inhibited by specific drug ligands.

Keyphrases

induced apoptosis
cell cycle arrest
endothelial cells
emergency department
high glucose
cell death
signaling pathway
oxidative stress
computed tomography
stress induced