Comparison of Immunogenicity and Safety of Inactivated, Adenovirus-Vectored, and Heterologous Adenovirus-Vectored/mRNA Vaccines in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Prospective Cohort Study.

Theerada AssawasaksakulTanat LertussavavivatSeelwan SathitratanacheewinNont OudomyingPreeyaporn VichaiwattanaNasamon WanlapakornYong PoovorawanYingyos AvihingsanonNawaporn AssawasaksakulSupranee BuranapraditkunWonngarm Kittanamongkolchai

Published in: Vaccines (2022)

Adenovirus-vectored and adenovirus-vectored/mRNA vaccines elicited a stronger humoral and cellular immune response than inactivated vaccines, suggesting that they may be more suitable in SLE and RA patients receiving immunosuppressive therapy.

Keyphrases

immune response
rheumatoid arthritis
disease activity
gene therapy
systemic lupus erythematosus
ankylosing spondylitis
dendritic cells
binding protein
inflammatory response
cell therapy
saccharomyces cerevisiae