Three dimensional texture analysis of noncontrast chest CT in differentiating solitary solid lung squamous cell carcinoma from adenocarcinoma and correlation to immunohistochemical markers.

• Significant findings of the study The model created by five selected textural feature parameters can differentiate solid SCC from AC without contrast media. The selected five texture feature parameters are correlated to the immunohistochemical markers P63 and P40. • What this study adds The textural feature parameters' model can identify SCC from AC without contrast media.