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Clinical presentation, maternal-fetal, and neonatal outcomes of early-onset versus late onset preeclampsia-eclampsia syndrome in a teaching hospital in a low-resource setting: A retrospective cohort study.

Hale TekaAwol YemaneHiluf Ebuy AbrahaEphrem BerheHabtom TadesseFanos GebruMohammedtahir YahyaYtbarek TadesseDaniel GebreMarta AbrhaBisrat TesfayAshenafi TekleTsega GebremariamBirhane AmareMohamedawel Mohamedniguss EbrahimYibrah Berhe ZelelowAfework Mulugeta
Published in: PloS one (2023)
The present study highlights the clinical differences between early versus late onset preeclampsia. Women with early-onset disease are at increased levels of unfavorable maternal outcomes. Perinatal morbidity and mortality were also increased significantly in women with early onset disease. Therefore, gestational age at the onset of the disease should be taken as an important indicator of the severity of the disease with unfavorable maternal, fetal, and neonatal outcomes.
Keyphrases
  • early onset
  • late onset
  • birth weight
  • gestational age
  • pregnancy outcomes
  • pregnant women
  • metabolic syndrome
  • adipose tissue
  • insulin resistance
  • skeletal muscle
  • glycemic control