Maternal Lifestyle and Prenatal Risk Factors for Childhood Leukemia: A Review of the Existing Evidence.
Leticia BenítezSara Castro-BarqueroFàtima CrispiLina YoussefFrancesca CrovettoUte FischerErsen KameriClara BuenoMireia CamosPablo MenéndezMerja HeinäniemiArndt BorkhardtEduard GratacósPublished in: Fetal diagnosis and therapy (2024)
Parental age, ethnicity, maternal diet, folate intake, alcohol consumption, X-ray exposure, pesticides, perinatal infections, and fetal growth may have a significant role in the appearance of preleukemic lesions during fetal life. Dedicating efforts to studying maternal lifestyle during pregnancy and its association with genetic lesions leading to childhood leukemia could lead to novel prevention strategies.
Keyphrases
- alcohol consumption
- birth weight
- physical activity
- weight loss
- pregnancy outcomes
- pregnant women
- metabolic syndrome
- acute myeloid leukemia
- bone marrow
- cardiovascular disease
- risk assessment
- early life
- high resolution
- gestational age
- genome wide
- magnetic resonance
- quality improvement
- computed tomography
- childhood cancer
- gene expression
- mass spectrometry