Evaluation of a fully automated von Willebrand factor assay panel for the diagnosis of von Willebrand disease.

Francesca StufanoLuciano BaroncianiPaolo BucciarelliMarco BoscarinoPaola ColpaniMaria Teresa Pagliari Flora Peyvandi

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2020)

The AcuStar panel offers a good performance in the differential diagnosis between VWD type 1 and 2A/2B patients. A high rate of coincidence with historical diagnosis was obtained for VWD types 3, 2A/2B and 1. Even though in some cases more tests (eg, RIPA/multimeric analysis) are needed to complete an accurate VWD classification, the AcuStar panel is considered a sensitive, rapid and reliable tool to diagnose VWD patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
high throughput
mass spectrometry