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Unlocking the Potential of Bacteriophage to Prevent Recurrent Urinary Tract Infections after Kidney Transplantation.

John R LeeMichael J Satlin
Published in: Antimicrobial agents and chemotherapy (2023)
Recurrent urinary tract infections (UTIs) are common in kidney transplant recipients, and novel prevention approaches are needed. The case presented by Le et al. (Antimicrob Agents Chemother, in press) describes a patient with recurrent UTIs due to extended-spectrum β-lactamase-producing Klebsiella pneumoniae who was successfully treated with bacteriophage therapy. This commentary highlights the potential for bacteriophage therapy to prevent recurrent UTIs, as well as outstanding questions that require further investigation.
Keyphrases
  • urinary tract infection
  • klebsiella pneumoniae
  • multidrug resistant
  • escherichia coli
  • stem cells
  • human health
  • case report
  • risk assessment
  • mesenchymal stem cells
  • smoking cessation
  • replacement therapy