Highly luminescent gold nanocluster assemblies for bioimaging in living organisms.
Fanfan YuZheng CaoShiyu HeHui XiangGan ZhaoLina YangHonglin LiuPublished in: Chemical communications (Cambridge, England) (2022)
Fluorescent gold nanoclusters are promising nanomaterials for biomedical applications but confronted with low emission efficiency and poor surface functionality. Herein, three kinds of highly luminescent and functionalized gold nanocluster nano-assembled structures were fabricated by poly- l -arginine surface engineering for luminescence improvement. The assembly is employed for imaging the glutathione molecule in cells and living organisms with low background and high sensitivity.
Keyphrases
- quantum dots
- sensitive detection
- energy transfer
- high resolution
- induced apoptosis
- silver nanoparticles
- gram negative
- nitric oxide
- cell cycle arrest
- fluorescent probe
- living cells
- endoplasmic reticulum stress
- oxidative stress
- cell death
- mass spectrometry
- signaling pathway
- label free
- cell proliferation
- metal organic framework
- fluorescence imaging
- simultaneous determination
- solid state
- tandem mass spectrometry
- single molecule