Preclinical Effects Of Melatonin On The Development Of Ehrlich's Tumor: A Biochemical, Cognitive, And Molecular Approach.
Ivan Pereira LopesBianca Souza BagatelaAndrey Pereira LopesElaine Ferreira SilveiraGiuliana PetriJosé Francisco Ramos SantosMatheus Moreira PerezGlaucia Luciano da VeigaBeatriz da Costa Aguiar AlvesFábio Ferreira PerazzoDavid FederFernando Luiz Affonso FonsecaPublished in: Recent patents on anti-cancer drug discovery (2023)
In animals with Ehrlich´s tumor treated with melatonin, a decrease in oxidative stress, an amelioration in welfare and in cognitive tasks could be observed, even if the treatment has not reduced the size of the tumor itself. In parallel with the already patented use of melatonin in the treatment of sleep disorders or chronic kidney disease, our results propose its use to improve the general well-being of breast cancer patients.