Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells.

Rajagopal N Aravalli Daniel P CollinsJoel H HapkeAndrew T CraneClifford J Steer

Published in: Hepatic medicine : evidence and research (2020)

Our data strongly suggest that marmoset HLCs possess characteristics similar to those of PHHs. They could, therefore, be invaluable for studies on drug metabolism and cell transplantation therapy for a variety of liver disorders. Because of the similarities in the anatomical and physiological features of the common marmoset to that of humans, Callithrix jacchus is an appropriate animal model to study human disease conditions and cellular functions.

Keyphrases

embryonic stem cells
endothelial cells
electronic health record
induced pluripotent stem cells
big data
emergency department