Urinary Cyclophilin A and serum Cystatin C as biomarkers for diabetic nephropathy in children with type 1 diabetes.

Nanees Abdel-Badie SalemRania Mostafa El HelalyIbrahim Maroof AliHala Abd Alem EbrahimMostafa Mahmoud AlayootiHuda Ahmed El DomiatyHadil Mohamed Aboelenin

Published in: Pediatric diabetes (2020)

sCysC is a promising early biomarker for DN in childhood T1DM before albuminuria detection. eGFR-CysC is superior to eGFR-Cr in evaluating renal status in childhood T1DM. uCypA and uCypA/Cr were useful tools in predicting microalbuminuria, although not regarded as diagnostic biomarkers for early-stage DN in T1DM children by the current study.

Keyphrases

diabetic nephropathy
early stage
small cell lung cancer
epidermal growth factor receptor
young adults
tyrosine kinase
childhood cancer
early life
glycemic control
metabolic syndrome
radiation therapy
squamous cell carcinoma
lymph node
label free
quantum dots