Sanguinarine suppresses migration and metastasis in colorectal carcinoma associated with the inversion of EMT through the Wnt/β-catenin signaling.

Man ZhuZhengyan GongQing WuXianpeng ShiQi SuYanmin Zhang

Published in: Clinical and translational medicine (2020)

Taken together, the antimetastatic potential of SG attributed to the suppression of the Wnt/β-catenin signaling, which further prevented EMT progression. SG may be of value in a potential therapy for the management of metastasis CRC.

Keyphrases

epithelial mesenchymal transition
stem cells
cell proliferation
human health
signaling pathway
magnetic resonance
computed tomography