Combination of 2 Quantitative Immunoassays and Clinical Score Algorithm to Reduce False-Negative Results in Heparin-Induced Thrombocytopenia: Prevalence Study of Mauriziano Hospital in Turin, Italy.
Veronica MineiPaolo ValesellaMaria PapandreaPiera SiveraAntonio InsanaDomenico CossedduJohanna UmurungiBarbara MontaruliPublished in: The journal of applied laboratory medicine (2024)
Our prevalence was 3.1%, comparable with the literature. The approach combining 2 quantitative immunoassays' (CliA and ELISA) results and 4Ts score probability was able to rule out the diagnosis within 1 h in 66% of patients with suspected HIT and within 24 h in 88% of patients. In the remaining 12% of cases, management decisions have to be based on individualized judgment while awaiting functional confirming results (48-72 h).
Keyphrases
- end stage renal disease
- risk factors
- ejection fraction
- systematic review
- newly diagnosed
- chronic kidney disease
- machine learning
- peritoneal dialysis
- healthcare
- deep learning
- prognostic factors
- diabetic rats
- emergency department
- drug induced
- growth factor
- patient reported outcomes
- adverse drug
- electronic health record
- monoclonal antibody